Michal Pechoucek has been involved in establishing several successful technology start-ups, such as cybersecurity company Cognitive Security (acquired by CISCO in 2013), AgentFly Technologies, which focuses on autonomous air traffic control, and BlindSpot Solutions, which develops artificial intelligence for use in industry and which was acquired by the Adastra Group in 2017. From 2019 until 2024, he was appointed Chief Technology Officer (CTO) in Gen (Avast).

During his tenure as CTO at Gen (formerly Avast), the company achieved significant milestones. In 2021, Avast merged with NortonLifeLock in a deal valued at over $8 billion, creating one of the largest consumer cybersecurity companies globally. Prior to the merger, Avast was a FTSE 100 company listed on the London Stock Exchange, with a market capitalization of approximately $7.2 billion. Under Pechoucek's technical leadership, the company enhanced its AI and machine learning capabilities, particularly in threat detection and privacy protection.

As Director of the AI Center at the Czech Technical University in Prague, Michal Pechoucek has authored over 400 publications in AI research. He led the Department of Computer Science, co-founded Open Informatics, and launched http://prg.ai/ to establish Prague as an AI hub. His academic career includes visiting professorships at USC, Edinburgh, SUNY Binghamton, and Calgary, along with research projects for NASA, FAA, and the U.S. Department of Defense.

He is married and has three daughters. In his free time, he loves to hike in the mountains and run marathons.